It depends, of course. There may be trusted friends and family with whom you choose to be very open. With some of them, it will prove costly, as the very ones you confidently believed would be understanding and have your back will turn on you, while others you least expected will come to your defense!
However, most of the time, for most folks, we want to find some non-confrontive, non-rude way of responding to their own rude intrusiveness by saying, "None o' yer d--n business! Now get outa my face!", right? Is there a way to do that? To defuse the situation without letting them in? As it happens, there is.
4 Magic Phrases You Can Use to Respond to ANYTHING is likely to help you out tremendously.
If you have more or better answers to offer, please let us know, so we can post them here as well.